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CD200 (Mouse Anti-Human CD200R

Myeloid cells, OX2, OX2R, Ig superfamily domain

Myeloid cells like macrophages, mast cells and microglia protect the body against infection and harmful antigens but they are also involved in process such as pregnancy and wound repair. Such a variety of roles suggests that these cells are modulated by intricate communication mechanisms. By understanding these process, it may be possible to develop drugs that regulate myeloid cells to function in a certain way, thereby effectively, exerting some control on immunity.